Last month (May, 2018) I wrote about a new study published in Iran that looked at the "neuroprotective effects" effects of virgin coconut oil for Alzheimer's patients. The title of the study is Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat and was published in the journal Food and Chemical Toxicology. While we have been publishing reports of coconut oil reversing the symptoms of Alzheimer's Disease and other neurological diseases for several years now, we believe this was the first peer-reviewed study to actually look at some of the mechanisms of how coconut oil benefits Alzheimer's patients. Now, a second peer-reviewed study has been published here in 2018 looking at the mechanisms of how coconut oil positively affects Alzheimer's patients. Published in the journal, Neurochemical Research, researchers in Japan examined the effects of lauric acid, the most predominant medium chain fatty acid found in coconut oil, on activated microglia in mice. Coconut oil is nature's richest source of lauric acid at about 50% of its composition, and human breast milk comes in a distant second at around 6% lauric acid. The title of the study is Lauric Acid Alleviates Neuroinflammatory Responses by Activated Microglia: Involvement of the GPR40-Dependent Pathway.
A study published September 2017 by researchers from the Department of Pharmacy, Health and Nutritional Sciences, at the University of Calabria in Rende, Italy, and from the Department of Health Sciences at the University Magna Graecia in Catanzaro, Italy, looked at the anti-cancer activity of lauric acid, the main fatty acid found in coconut oil. While coconut oil continues to get slandered in the U.S. by those with close ties to the pharmaceutical industry, research mainly outside the U.S. continues to show how healthy coconut oil can be, dispelling the common saturated-fat-is-bad myth still being promoted in the U.S. The study title is: "The lauric acid-activated signaling prompts apoptosis in cancer cells," and it was published in the journal "Cell Death Recovery." The study looked at the effects of lauric acid in both breast cancer and colon cancer: "The saturated medium-chain fatty-acid lauric acid (LA) has been associated to certain health-promoting benefits of coconut oil intake, including the improvement of the quality of life in breast cancer patients during chemotherapy. As it concerns the potential to hamper tumor growth, LA was shown to elicit inhibitory effects only in colon cancer cells. Here, we provide novel insights regarding the molecular mechanisms through which LA triggers antiproliferative and pro-apoptotic effects in both breast and endometrial cancer cells." Coconut oil is nature's richest source of lauric acid, by far, comprising almost 50% of the fatty acids in coconut oil. Human breast milk comes in a distant second at around 6% lauric acid. Lauric acid has a rich and long history of fighting pathogens, and has been a popular food preservative for many decades. Perhaps the most significant observation documented in this study was the ability of lauric acid to target cancer cells but not affect healthy cells, unlike most chemotherapy drugs: "Lauric Acid inhibited the viability of both cancer cell types without altering the growth of MCF-10A normal breast epithelial cells, thus suggesting its specific potential to trigger antiproliferative effects in malignant cells."
There have been numerous studies on lauric acid for various health supporting factors. Did you know that virgin coconut oil is 50 percent or more lauric acid? So whatever healthy attributes lauric acid contains so does coconut oil, and more. And more will be explained later in this article. For now we’ll focus on coconut oil’s major component, lauric acid, and a recent animal study with dramatic results discovered for reducing hypertension (high blood pressure) and oxidative stress.