Hippocrates, the ancient Greek doctor, is often quoted as saying, "All disease begins in the gut." This includes many diseases not currently associated (by modern medical practitioners) with gastrointestinal (GI) tract issues, although there is a small contingent of progressive practitioners who are recognizing this phenomenon. Dysbiosis is the imbalance of intestinal gut flora or gut microbiome (the symbiotic bacteria occurring naturally in the intestines) that seems to be the foundation of gut diseases: Crohn’s disease, IBD (irritable bowel disease), and IBS (irritable bowel syndrome). There has been a steady increase of various gastrointestinal (GI) tract diseases and disorders occurring throughout the U.S. over the past few decades. The popular scapegoat for the rise in GI tract disease is grains, specifically gluten, but much of that blame is misplaced. In this article we will look at common causes of gut dysbiosis, and how one can prevent or even reverse leaky gut disorders.