A ketogenic diet — which is very low in net carbohydrates and high in healthy fats — is key for boosting mitochondrial function. Healthy fats also play an important role in maintaining your body's electrical system. When your body is able to burn fat for fuel, your liver creates water-soluble fats called ketones that burn far more efficiently than carbs, thereby creating fewer reactive oxygen species (ROS) and secondary free radicals. Ketones also decrease inflammation, improve glucose metabolism and aid the building of muscle mass. The benefits of a cyclical ketogenic diet are detailed in my latest bestselling book, "Fat for Fuel." While the book was peer-reviewed by over a dozen health experts and scientists, a new large-scale international study (known as the international Prospective Urban Rural Epidemiology, or PURE, study) adds further weight to the premise that high intakes of healthy fats — especially saturated fats — boost health and longevity.
In 1931, Dr. Otto Warburg won the Nobel Prize Physiology or Medicine for his discovery that cancer cells have a fundamentally different energy metabolism compared to healthy cells. Most experts consider him to be the greatest biochemist of the 20th century. His lab staff also included Hans Krebs, Ph.D., after whom the Krebs cycle was named. The Krebs cycle refers to the oxidative reduction pathways that occur in the mitochondria. So just how does the metabolic inflexibility of cancer cells differ from healthy cells? A cell can produce energy in two ways: aerobically, in the mitochondria, or anaerobically, in the cytoplasm, the latter of which generates lactic acid — a toxic byproduct. Warburg discovered that in the presence of oxygen, cancer cells overproduce lactic acid. This is known as The Warburg Effect. Mitochondrial energy production is far more efficient, capable of generating 18 times more energy in the form of adenosine triphosphate (ATP) than anaerobic energy generation. Warburg concluded that the prime cause of cancer was the reversion of energy production from aerobic energy generation to a more primitive form of energy production, anaerobic fermentation. To reverse cancer, he believed you had to disrupt the energy production cycle that is feeding the tumor, and that by reverting back to aerobic energy metabolism you could effectively "starve" it into remission. Although he was never able to conclusively prove it, he maintained this view until his death in 1970. One of his goals in life was to discover the cure for cancer. Sadly, as so typically happens in science, his theories were never accepted by conventional science despite his academic pedigree — until now. The New York Times recently published a long, detailed article about the history of modern cancer research, including Warburg's theories on cancer, which are now becoming more widely accepted.
A high-fat low-carb ketogenic diet can optimize your metabolism. Numerous studies have shown that lowering your caloric intake may slow down aging, help prevent age-related chronic diseases, and extend your life.
Sweden Becomes First Western Nation to Reject Low-fat Diet Dogma in Favor of Low-carb High-fat Nutrition
Sweden has become the first Western nation to develop national dietary guidelines that reject the popular low-fat diet dogma in favor of low-carb high-fat nutrition advice.
Governments here and abroad have been cautioning the public for decades on the dangers of high fat diets. The fact is, contrary to official advice by our diet dictocrats, high-fat diets lower blood sugar, improve blood lipids, and reduce obesity.
There are long-term studies on the effects of a high fat diet, and one of them is on the US Government's website.